Crash Course on Risk Assessment: Organic Agents, Metals, Nanoparticles
09:00 - 17:00
Led by: Andrey Korchevskiy, PhD, CIH, DABT
Andrey Korchevskiy, PhD, DABT, CIH, is a Director of Research and Development in C&IH (Wheat Ridge, Colorado). He is a specialists in risk assessment modeling for industrial hygiene and environmental health applications. Andrey is a certified toxicologist (DABT) and certified industrial hygienist (CIH). He arranged and taught risk assessment classes in the US, UK, Canada, Mexico, Colombia, and other countries. He has over 150 scientific publications in the fields of industrial hygiene, epidemiology, toxicology, and biostatistics. He is a full member of the Society of Toxicology (SOT). He is a Distinguished Lecturer of the AIHA, a recipient of AIHA Outstanding Project Team Award, AIHA Volunteer Group Service Award -2016, and SOT International ToxScholar grant.
Andrew Darnton, MSc, is one of the leading internationally renown epidemiologists, famous for his landmarks publications on asbestos health risk assessment. He is a statistician at the HSE, UK.
Bruce Case, MD, is a pathologist and epidemiologist at McGill University, Canada, one of the most advanced experts in the area of asbestos pathology. He has been a member of BOHS since 1985. From 1988-1991, he served as Director of the United States Environmental Protection Agency Center for Environmental Epidemiology (University of Pittsburgh School of Public Health). He provided peer reviews, professional development courses, lectures, workshops, and advice for national and international agencies and professional societies regarding exposure assessment for health effects of mineral fibres and particles, including NIOSH, USEPA, ATSDR, IARC, ICOH, BOHS, ATS, GSA, Collegium Ramazzini, and others.
Jim Rasmuson, PhD, CIH, DABT, FAIHA (USA), is a CEO and senior scientist at Chemistry & Industrial Hygiene, Inc. He developed numerous published works, presentations and classes in exposure and risk assessment, industrial hygiene, retrospective exposure assessment, simulation testing, analytical chemistry, laboratory methods development, regulatory compliance, and quality assurance.
Risk assessment is an essential tool used in the occupational hygiene profession. Occupational hygienists use risk assessment to establish internal occupational exposure limits, predict health outcomes of exposure for certain groups of workers, and deal with new and emerging hazardous compounds. Occupational and environmental health experts should be aware of the most up-to-date risk assessment techniques, so they can take advantage of these methods as part of their professional expertise. This PDC will take participants for an intensive one-day ride exploring how and when they can use risk assessment methods.
The objective of the class is to demonstrate different methods and approaches used for risk assessment purposes. Structural components of the risk assessment paradigm (hazard identification, exposure assessment, dose-response assessment, and risk characterization) will be described from a practical point of view. The participants will learn through class exercises how to obtain and interpret risk metrics, including: absolute and relative risk, attributable risk fraction, unit risk, slope factor, reference concentration and dose, and other metrics. The audience will participate in exciting and interactive exercises, including a statistical risk simulation demonstrating the probabilistic nature of hazards and health outcomes. “Risk taking behavior” characteristics of the audience will be tested and analyzed: a method that can be useful for individual risk assessment at workplaces. The class will be based on case studies which are intended to refresh the audience’s knowledge on numerous hazardous agents including, but not limited to, glyphosate, acrylamide, benzene, beryllium, cadmium, and nanoparticles. The participants also will learn methods to develop hypothetical internal standards to protect workers from adverse health effects.
Intermediate level education and experience in environmental and/or occupational health exposure assessment is required. Some risk assessment background a plus.
1. Interpret basic definitions and metrics of risk assessment.
2. Discuss 4 -steps risk assessment paradigm and its advantages.
3. Utilize statistical simulation for exposure and risk calculations.
4. Calculate absolute and relative carcinogenic risk values based on slope factors and unit risks.
5. Search for relevant risk assessment information.
6. Interpret excess risk values based on the various risk acceptability criteria.
7. Derive internal standards from available risk assessment information.
8. Communicate risk assessment procedure and its results in unified way.
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